<p> During the process of <taxon tax_id="562">Escherichia coli</taxon> nucleotide excision repair, DNA damage recognition and processing are achieved by the action of the uvrA, uvrB, and uvrC gene products [<cite idref="PUB00006064"/>]. The C-terminal domain of UvrB binds to a homologous domain in UvrC, possibly by specific hydrophobic and salt bridge interactions [<cite idref="PUB00013189"/>]. This domain forms two helices in an antiparallel hairpin fold with a left-handed twist. This interaction is important for the incision of the damaged strand [<cite idref="PUB00006065"/>].</p> UvrB, C-terminal UvrC-binding